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Early Decline in Glucose Transport and Metabolism Precedes Shift to Ketogenic System in Female Aging and Alzheimer's Mouse Brain: Implication for Bioenergetic Intervention

We previously demonstrated that mitochondrial bioenergetic deficits in the female brain accompanied reproductive senescence and was accompanied by a shift from an aerobic glycolytic to a ketogenic phenotype. Herein, we investigated the relationship between systems of fuel supply, transport and mitoc...

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Autores principales: Ding, Fan, Yao, Jia, Rettberg, Jamaica R., Chen, Shuhua, Brinton, Roberta Diaz
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823655/
https://ncbi.nlm.nih.gov/pubmed/24244584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079977
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