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Orbital Fibroblasts From Thyroid Eye Disease Patients Differ in Proliferative and Adipogenic Responses Depending on Disease Subtype

PURPOSE. Thyroid eye disease (TED) patients are classified as type I (predominantly fat compartment enlargement) or type II (predominantly extraocular muscle enlargement) based on orbital imaging. Orbital fibroblasts (OFs) can be driven to proliferate or differentiate into adipocytes in vitro. We te...

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Detalhes bibliográficos
Main Authors: Kuriyan, Ajay E., Woeller, Collynn F., O'Loughlin, Charles W., Phipps, Richard P., Feldon, Steven E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823547/
https://ncbi.nlm.nih.gov/pubmed/24135759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-12741
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