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Inhibition of IKKß in enterocytes exacerbates sepsis-induced intestinal injury and worsens mortality
OBJECTIVE: NF-kB is a critical regulator of cell survival genes and the host inflammatory response. The purpose of this study was to investigate the role of enterocyte-specific NF-kB in sepsis through selective ablation of IkB kinase (IKK)-ß. DESIGN: Prospective, randomized, controlled study. SETTIN...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3823541/ https://ncbi.nlm.nih.gov/pubmed/23939348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e31828a44ed |
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