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Enterocyte-specific epidermal growth factor prevents barrier dysfunction and improves mortality in murine peritonitis

Systemic administration of epidermal growth factor (EGF) decreases mortality in a murine model of septic peritonitis. Although EGF can have direct healing effects on the intestinal mucosa, it is unknown whether the benefits of systemic EGF in peritonitis are mediated through the intestine. Here, we...

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Main Authors: Clark, Jessica A., Gan, Heng, Samocha, Alexandr J., Fox, Amy C., Buchman, Timothy G., Coopersmith, Craig M.
格式: Artigo
語言:Inglês
出版: American Physiological Society 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739816/
https://ncbi.nlm.nih.gov/pubmed/19571236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00012.2009
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