Enterocyte-specific epidermal growth factor prevents barrier dysfunction and improves mortality in murine peritonitis

Systemic administration of epidermal growth factor (EGF) decreases mortality in a murine model of septic peritonitis. Although EGF can have direct healing effects on the intestinal mucosa, it is unknown whether the benefits of systemic EGF in peritonitis are mediated through the intestine. Here, we...

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Detalhes bibliográficos
Main Authors: Clark, Jessica A., Gan, Heng, Samocha, Alexandr J., Fox, Amy C., Buchman, Timothy G., Coopersmith, Craig M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Mucosal Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739816/
https://ncbi.nlm.nih.gov/pubmed/19571236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00012.2009
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