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Epidermal growth factor treatment decreases mortality and is associated with improved gut integrity in sepsis

Epidermal growth factor (EGF) is a cytoprotective peptide that has healing effects on the intestinal mucosa. We sought to determine whether systemic administration of EGF following the onset of sepsis improved intestinal integrity and decreased mortality. FVB/N mice were subjected to either sham lap...

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Detalhes bibliográficos
Main Authors: Clark, Jessica A., Clark, Andrew T., Hotchkiss, Richard S., Buchman, Timothy G., Coopersmith, Craig M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2551558/
https://ncbi.nlm.nih.gov/pubmed/18004230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/shk.0b013e31815D0820
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