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Intestine-specific overexpression of IL-10 improves survival in polymicrobial sepsis

Targeted Interleukin (IL)-10 therapy improves survival in preclinical models of critical illness, and intestine-specific IL-10 decreases inflammation in models of chronic inflammatory disease. We therefore sought to determine whether intestine-specific overexpression of IL-10 would improve survival...

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Detalhes bibliográficos
Main Authors: Rajan, Saju, Vyas, Dinesh, Clark, Andrew T, Woolsey, Cheryl A, Clark, Jessica A, Hotchkiss, Richard S, Buchman, Timothy G, Coopersmith, Craig M
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562881/
https://ncbi.nlm.nih.gov/pubmed/17998890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/shk.0b013e31815bbb26
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