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Loss of CCM3 impairs DLL4-Notch signalling: implication in endothelial angiogenesis and in inherited cerebral cavernous malformations

CCM3, a product of the cerebral cavernous malformation 3 or programmed cell death 10 gene (CCM3/PDCD10), is broadly expressed throughout development in both vertebrates and invertebrates. Increasing evidence indicates a crucial role of CCM3 in vascular development and in regulation of angiogenesis a...

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Detalhes bibliográficos
Main Authors: You, Chao, Erol Sandalcioglu, Ibrahim, Dammann, Philipp, Felbor, Ute, Sure, Ulrich, Zhu, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823022/
https://ncbi.nlm.nih.gov/pubmed/23388056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12022
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