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Implications of Dll4-Notch signaling activation in primary glioblastoma multiforme

BACKGROUND: Glioblastoma multiforme (GBM) is a highly aggressive brain tumor characterized by massive neovascularization, necrosis, and intense resistance to therapy. Deregulated Notch signaling has been implicated in the formation and progression of different malignancies. The present study attempt...

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Detalhes bibliográficos
Main Authors: El Hindy, Nicolai, Keyvani, Kathy, Pagenstecher, Axel, Dammann, Philip, Sandalcioglu, I. Erol, Sure, Ulrich, Zhu, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779034/
https://ncbi.nlm.nih.gov/pubmed/23787764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not071
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