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AMP-activated protein kinase and pancreatic/duodenal homeobox-1 involved in insulin secretion under high leucine exposure in rat insulinoma β-cells

The effect of leucine on glucose-stimulated insulin secretion (GSIS) in pancreatic β-cells is quite controversial, and mechanism involved in the effect has not been elucidated yet. Consequently, we aimed to investigate effect of leucine on GSIS and its mechanism focusing on contribution of AMP-activ...

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Detalhes bibliográficos
Main Authors: Zhang, Xiujuan, Sun, Nannan, Wang, Laicheng, Guo, Hua, Guan, Qingbo, Cui, Bin, Tian, Limin, Gao, Ling, Zhao, Jiajun
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822882/
https://ncbi.nlm.nih.gov/pubmed/19438972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00656.x
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