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Progranulin contributes to endogenous mechanisms of pain defense after nerve injury in mice

Progranulin haploinsufficiency is associated with frontotemporal dementia in humans. Deficiency of progranulin led to exaggerated inflammation and premature aging in mice. The role of progranulin in adaptations to nerve injury and neuropathic pain are still unknown. Here we found that progranulin is...

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Detalles Bibliográficos
Main Authors: Lim, Hee-Young, Albuquerque, Boris, Häussler, Annett, Myrczek, Thekla, Ding, Aihao, Tegeder, Irmgard
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822842/
https://ncbi.nlm.nih.gov/pubmed/21645236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2011.01350.x
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