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Progranulin promotes peripheral nerve regeneration and reinnervation: role of notch signaling
BACKGROUND: Peripheral nerve injury is a frequent cause of lasting motor deficits and chronic pain. Although peripheral nerves are capable of regrowth they often fail to re-innervate target tissues. RESULTS: Using newly generated transgenic mice with inducible neuronal progranulin overexpression we...
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Publicado no: | Mol Neurodegener |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5075406/ https://ncbi.nlm.nih.gov/pubmed/27770818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0132-1 |
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