Progranulin promotes peripheral nerve regeneration and reinnervation: role of notch signaling

BACKGROUND: Peripheral nerve injury is a frequent cause of lasting motor deficits and chronic pain. Although peripheral nerves are capable of regrowth they often fail to re-innervate target tissues. RESULTS: Using newly generated transgenic mice with inducible neuronal progranulin overexpression we...

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Vydáno v:Mol Neurodegener
Hlavní autoři: Altmann, Christine, Vasic, Verica, Hardt, Stefanie, Heidler, Juliana, Häussler, Annett, Wittig, Ilka, Schmidt, Mirko H. H., Tegeder, Irmgard
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075406/
https://ncbi.nlm.nih.gov/pubmed/27770818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0132-1
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