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Cooperative effects of Janus and Aurora kinase inhibition by CEP701 in cells expressing Jak2V617F
The Janus kinase 2 mutant V617F occurs with high frequency in myeloproliferative neoplasms. Further mutations affecting the Janus kinase family have been discovered mostly in leukaemias and in myeloproliferative neoplasms. Owing to their involvement in neoplasia, inflammatory diseases and in the imm...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3822589/ https://ncbi.nlm.nih.gov/pubmed/23301855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12005 |
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