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Polymorphisms in p53 and the p53 pathway: roles in cancer susceptibility and response to treatment

The p53 tumour suppressor protein lies at the crossroads of multiple cellular response pathways that control the fate of the cell in response to endogenous or exogenous stresses and inactivation of the p53 tumour suppressor signalling pathway is seen in most human cancers. Such aberrant p53 activity...

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Bibliografische gegevens
Hoofdauteurs: Hrstka, Roman, Coates, Philip J, Vojtesek, Borivoj
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822507/
https://ncbi.nlm.nih.gov/pubmed/19379143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00634.x
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