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Metformin attenuates ovarian cancer cell growth in an AMP-kinase dispensable manner

Metformin, the most widely used drug for type 2 diabetes activates 59 adenosine monophosphate (AMP)-activated protein kinase (AMPK), which regulates cellular energy metabolism. Here, we report that ovarian cell lines VOSE, A2780, CP70, C200, OV202, OVCAR3, SKOV3ip, PE01 and PE04 predominantly expres...

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Autors principals: Rattan, R, Giri, S, Hartmann, LC, Shridhar, V
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822503/
https://ncbi.nlm.nih.gov/pubmed/19874425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00954.x
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