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Metformin Suppresses Ovarian Cancer Growth and Metastasis with Enhancement of Cisplatin Cytotoxicity In Vivo

Ovarian cancer is the most lethal gynecologic cancer in women. Its high mortality rate (68%) reflects the fact that 75% of patients have extensive (>stage III) disease at diagnosis and also the limited efficacy of currently available therapies. Consequently, there is clearly a great need to devel...

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Main Authors: Rattan, Ramandeep, Graham, Rondell P, Maguire, Jacie L, Giri, Shailendra, Shridhar, Viji
Format: Artigo
Jezik:Inglês
Izdano: Neoplasia Press Inc. 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084625/
https://ncbi.nlm.nih.gov/pubmed/21532889
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