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Cdc45 Is a Critical Effector of Myc-Dependent DNA Replication Stress
c-Myc oncogenic activity is thought to be mediated in part by its ability to generate DNA replication stress and subsequent genomic instability when deregulated. Previous studies have demonstrated a nontranscriptional role for c-Myc in regulating DNA replication. Here, we analyze the mechanisms by w...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3822004/ https://ncbi.nlm.nih.gov/pubmed/23643534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.04.002 |
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