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Phage Display to Identify Nedd8-mimicking Peptides as Inhibitors of the Nedd8 Transfer Cascade
The Nedd8 activating enzyme (NAE) launches the transfer of the ubiquitin-like protein Nedd8 through an enzymatic cascade to covalently modify a diverse array of proteins, thus regulating their biological functions in the cell. The C-terminal peptide of Nedd8 extends deeply into the active site of NA...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3822002/ https://ncbi.nlm.nih.gov/pubmed/23824602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201300234 |
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