A Potent Soluble Epoxide Hydrolase Inhibitor, t-AUCB, Acts Through PPARγ to Modulate the Function of Endothelial Progenitor Cells From Patients with Acute Myocardial Infarction

BACKGROUND: Epoxyeicosatrienoic acids (EETs) are natural angiogenic mediators regulated by soluble epoxide hydrolase (sEH). Inhibitors of sEH can stabilize EETs levels and were reported to reduce atherosclerosis and inhibit myocardial infarction in animal models. In this work, we investigated wether...

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Detalhes bibliográficos
Main Authors: Xu, Dan-yan, Davis, Benjamin B., Wang, Zhen-he, Zhao, Shui-ping, Wasti, Binaya, Liu, Zhe-liang, Li, Ning, Morisseau, Christophe, Chiamvimonvat, Nipavan, Hammock, Bruce D
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821736/
https://ncbi.nlm.nih.gov/pubmed/22525341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcard.2012.03.167
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