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Generation of an ICF Syndrome Model by Efficient Genome Editing of Human Induced Pluripotent Stem Cells Using the CRISPR System

Genome manipulation of human induced pluripotent stem (iPS) cells is essential to achieve their full potential as tools for regenerative medicine. To date, however, gene targeting in human pluripotent stem cells (hPSCs) has proven to be extremely difficult. Recently, an efficient genome manipulation...

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Detalhes bibliográficos
Main Authors: Horii, Takuro, Tamura, Daiki, Morita, Sumiyo, Kimura, Mika, Hatada, Izuho
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821585/
https://ncbi.nlm.nih.gov/pubmed/24084724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms141019774
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