Multidrug resistance mediated by a bacterial homolog of the human multidrug transporter MDR1.

Resistance of Lactococcus lactis to cytotoxic compounds shares features with the multidrug resistance phenotype of mammalian tumor cells. Here, we report the gene cloning and functional characterization in Escherichia coli of LmrA, a lactococcal structural and functional homolog of the human multidr...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	van Veen, H W, Venema, K, Bolhuis, H, Oussenko, I, Kok, J, Poolman, B, Driessen, A J, Konings, W N
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38212/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8855237/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.20.10668
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