Multidrug resistance mediated by a bacterial homolog of the human multidrug transporter MDR1.

Resistance of Lactococcus lactis to cytotoxic compounds shares features with the multidrug resistance phenotype of mammalian tumor cells. Here, we report the gene cloning and functional characterization in Escherichia coli of LmrA, a lactococcal structural and functional homolog of the human multidr...

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Autors principals: van Veen, H W, Venema, K, Bolhuis, H, Oussenko, I, Kok, J, Poolman, B, Driessen, A J, Konings, W N
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC38212/
https://ncbi.nlm.nih.gov/pubmed/8855237
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