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Ligand Binding Site Detection by Local Structure Alignment and Its Performance Complementarity

Accurate determination of potential ligand binding sites (BS) is a key step for protein function characterization and structure-based drug design. Despite promising results of template-based BS prediction methods using global structure alignment (GSA), there is a room to improve the performance by p...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Lee, Hui Sun, Im, Wonpil
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821077/
https://ncbi.nlm.nih.gov/pubmed/23957286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci4003602
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