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Identification of Ligand Templates using Local Structure Alignment for Structure-based Drug Design

With a rapid increase in the number of high-resolution protein-ligand structures, the known protein-ligand structures can be used to gain insight into ligand-binding modes in a target protein. Based on the fact that the structurally similar binding sites share information about their ligands, we hav...

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Bibliografski detalji
Glavni autori: Lee, Hui Sun, Im, Wonpil
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478504/
https://ncbi.nlm.nih.gov/pubmed/22978550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci300178e
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