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Spermidine Stimulates T Cell Protein-tyrosine Phosphatase-mediated Protection of Intestinal Epithelial Barrier Function

The gene locus encoding protein-tyrosine phosphatase non-receptor type 2 (PTPN2) has been associated with inflammatory bowel disease. Expression of the PTPN2 gene product, T cell protein-tyrosine phosphatase (TCPTP), in intestinal epithelial cells has been shown to play an important role in the prot...

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Détails bibliographiques
Auteurs principaux: Penrose, Harrison M., Marchelletta, Ronald R., Krishnan, Moorthy, McCole, Declan F.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820900/
https://ncbi.nlm.nih.gov/pubmed/24022492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.475962
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