Interferon-γ Alters Downstream Signaling Originating from Epidermal Growth Factor Receptor in Intestinal Epithelial Cells: FUNCTIONAL CONSEQUENCES FOR ION TRANSPORT

The epidermal growth factor receptor (EGFr) regulates many cellular functions, such as proliferation, apoptosis, and ion transport. Our aim was to investigate whether long term treatment with interferon-γ (IFN-γ) modulates EGF activation of downstream signaling pathways in intestinal epithelial cell...

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Detalhes bibliográficos
Main Authors: Paul, Gisela, Marchelletta, Ronald R., McCole, Declan F., Barrett, Kim E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265893/
https://ncbi.nlm.nih.gov/pubmed/22069319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.318139
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