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Structural Basis for the Different Stability and Activity between the Cdk5 Complexes with p35 and p39 Activators
Cyclin-dependent kinase 5 (Cdk5) is a brain-specific membrane-bound protein kinase that is activated by binding to the p35 or p39 activator. Previous studies have focused on p35-Cdk5, and little is known regarding p39-Cdk5. The lack of functional understanding of p39-Cdk5 is due, in part, to the lab...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3820878/ https://ncbi.nlm.nih.gov/pubmed/24085300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.512293 |
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