The Homeobox Gene MEIS1 Is Methylated in BRAF (p.V600E) Mutated Colon Tumors

Development of colorectal cancer (CRC) can occur both via gene mutations in tumor suppressor genes and oncogenes, as well as via epigenetic changes, including DNA methylation. Site-specific methylation in CRC regulates expression of tumor-associated genes. Right-sided colon tumors more frequently ha...

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Autors principals: Dihal, Ashwin A., Boot, Arnoud, van Roon, Eddy H., Schrumpf, Melanie, Fariña-Sarasqueta, Arantza, Fiocco, Marta, Zeestraten, Eliane C. M., Kuppen, Peter J. K., Morreau, Hans, van Wezel, Tom, Boer, Judith M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820613/
https://ncbi.nlm.nih.gov/pubmed/24244575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079898
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