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Reactivation of death receptor 4 (DR4) expression sensitizes medulloblastoma cell lines to TRAIL

OBJECT: Apoptosis, a key cellular response to therapeutic agents is often inactivated in tumor cells. In this study, we evaluated the expression of the tumor necrosis family of death receptors, DR4 and DR5, in medulloblastoma tumor samples and cell lines to determine if epigenetic modulation of gene...

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Main Authors: Aguilera, Dolly G., Das, Chandra M., Sinnappah-Kang, Neeta D., Joyce, Celine, Taylor, Pete H., Wen, Sijin, Hasselblatt, Martin, Paulus, Werner, Fuller, Greg, Wolff, Johannes E., Gopalakrishnan, Vidya
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820292/
https://ncbi.nlm.nih.gov/pubmed/19148581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-008-9788-x
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