Reactivation of death receptor 4 (DR4) expression sensitizes medulloblastoma cell lines to TRAIL

OBJECT: Apoptosis, a key cellular response to therapeutic agents is often inactivated in tumor cells. In this study, we evaluated the expression of the tumor necrosis family of death receptors, DR4 and DR5, in medulloblastoma tumor samples and cell lines to determine if epigenetic modulation of gene...

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Autores principales: Aguilera, Dolly G., Das, Chandra M., Sinnappah-Kang, Neeta D., Joyce, Celine, Taylor, Pete H., Wen, Sijin, Hasselblatt, Martin, Paulus, Werner, Fuller, Greg, Wolff, Johannes E., Gopalakrishnan, Vidya
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820292/
https://ncbi.nlm.nih.gov/pubmed/19148581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-008-9788-x
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