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TRAIL-induced apoptosis in gliomas is enhanced by Akt-inhibition and is independent of JNK activation()
Patients with malignant gliomas have a poor prognosis and new treatment paradigms are needed against this disease. TRAIL/Apo2L selectively induces apoptosis in malignant cells sparing normal cells and is hence of interest as a potential therapeutic agent against gliomas. To determine the factors tha...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3820101/ https://ncbi.nlm.nih.gov/pubmed/15711939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-005-6078-3 |
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