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TRAIL-induced apoptosis in gliomas is enhanced by Akt-inhibition and is independent of JNK activation()

Patients with malignant gliomas have a poor prognosis and new treatment paradigms are needed against this disease. TRAIL/Apo2L selectively induces apoptosis in malignant cells sparing normal cells and is hence of interest as a potential therapeutic agent against gliomas. To determine the factors tha...

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Detalhes bibliográficos
Main Authors: Puduvalli, V. K., Sampath, D., Bruner, J. M., Nangia, J., Xu, R., Kyritsis, A. P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820101/
https://ncbi.nlm.nih.gov/pubmed/15711939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-005-6078-3
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