Shikonin sensitizes A549 cells to TRAIL-induced apoptosis through the JNK, STAT3 and AKT pathways

BACKGROUND: TRAIL, tumor necrosis factor-related apoptosis-inducing ligand, can selectively kill cancer cells with little or no cytotoxicity toward normal human cells and is regarded as a potential relatively safe antitumor drug. However, some cancer cells are resistant to TRAIL-induced apoptosis. T...

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Pubblicato in:BMC Cell Biol
Autori principali: Guo, Zhi Lan, Li, Jing Zhe, Ma, Yan Yan, Qian, Dan, Zhong, Ju Ying, Jin, Meng Meng, Huang, Peng, Che, Lu Yang, Pan, Bing, Wang, Yi, Sun, Zhen Xiao, Liu, Chang Zhen
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310954/
https://ncbi.nlm.nih.gov/pubmed/30594131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-018-0179-7
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