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Heat Shock Protein 90 Is Critical for Regulation of Phenotype and Functional Activity of Human T Lymphocytes and NK Cells

The 90-kDa heat shock protein (Hsp90) has become an important therapeutic target with ongoing evaluation in a number of malignancies. Although Hsp90 inhibitors have a high therapeutic index with limited effects on normal cells, they have been described to inhibit dendritic cell function. However, it...

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Библиографические подробности
Главные авторы: Bae, Jooeun, Munshi, Aditya, Li, Cheng, Samur, Mehmet, Rao, Prabhala, Mitsiades, Constantine, Anderson, Kenneth C., Munshi, Nikhil C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819808/
https://ncbi.nlm.nih.gov/pubmed/23293352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200593
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