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Molecular co-evolution of a protease and its substrate elucidated by analysis of the activity of predicted ancestral hatching enzyme

BACKGROUND: Hatching enzyme is a protease that digests the egg envelope, enabling hatching of the embryo. We have comprehensively studied the molecular mechanisms of the enzyme action to its substrate egg envelope, and determined the gene/protein structure and phylogenetic relationships. Because the...

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Autors principals: Kawaguchi, Mari, Inoue, Koji, Iuchi, Ichiro, Nishida, Mutsumi, Yasumasu, Shigeki
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819744/
https://ncbi.nlm.nih.gov/pubmed/24161109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-13-231
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