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Strategies to overcome the action of aminoglycoside-modifying enzymes for treating resistant bacterial infections

Shortly after the discovery of the first antibiotics, bacterial resistance began to emerge. Many mechanisms give rise to resistance; the most prevalent mechanism of resistance to the aminoglycoside (AG) family of antibiotics is the action of aminoglycoside-modifying enzymes (AMEs). Since the identif...

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Detalhes bibliográficos
Main Authors: Labby, Kristin J, Garneau-Tsodikova, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819198/
https://ncbi.nlm.nih.gov/pubmed/23859208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.13.80
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