META-ANALYSIS OF CYP2D6 METABOLIZER PHENOTYPE AND METOPROLOL PHARMACOKINETICS

Metoprolol, a commonly prescribed beta-blocker, is primarily metabolized by cytochrome P450 2D6 (CYP2D6), an enzyme with substantial genetic heterogeneity. Several smaller studies have shown that metoprolol pharmacokinetics is influenced by CYP2D6 genotype and metabolizer phenotype. To increase robu...

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Detaylı Bibliyografya
Asıl Yazarlar: Blake, CM, Kharasch, ED, Schwab, M, Nagele, P
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818912/
https://ncbi.nlm.nih.gov/pubmed/23665868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2013.96
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