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FTO gains function

Previous genome-wide association studies have identified a strong association between FTO and human obesity, although the mechanism by which FTO affects obesity remains unknown. Anew study suggests that the obesity risk alleles are gain-of-function.

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Bibliographische Detailangaben
Hauptverfasser: Stratigopoulos, George, Leibel, Rudolph L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818900/
https://ncbi.nlm.nih.gov/pubmed/21102620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1210-1038
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