The chromomycin CmmA acetyltransferase: a membrane‐bound enzyme as a tool for increasing structural diversity of the antitumour mithramycin

Mithramycin and chromomycin A(3) are two structurally related antitumour compounds, which differ in the glycosylation profiles and functional group substitutions of the sugars. Chromomycin contains two acetyl groups, which are incorporated during the biosynthesis by the acetyltransferase CmmA in Str...

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Autors principals: García, Beatriz, González‐Sabín, Javier, Menéndez, Nuria, Braña, Alfredo F., Núñez, Luz Elena, Morís, Francisco, Salas, José A., Méndez, Carmen
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2011
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818863/
https://ncbi.nlm.nih.gov/pubmed/21342468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1751-7915.2010.00229.x
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