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Regulation of epithelial plasticity by miR-424 and miR-200 in a new prostate cancer metastasis model
Using an in vivo cycling strategy, we selected metastatic cancer cells from the lymph nodes (LN) of mice bearing orthotopic DU145 human prostate tumors. Repeated rounds of metastatic selection (LN1–LN4) progressively increased the epithelial phenotype, resulting in a new model of tumor cell mesenchy...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3818652/ https://ncbi.nlm.nih.gov/pubmed/24193225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03151 |
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