Regulation of epithelial plasticity by miR-424 and miR-200 in a new prostate cancer metastasis model

Using an in vivo cycling strategy, we selected metastatic cancer cells from the lymph nodes (LN) of mice bearing orthotopic DU145 human prostate tumors. Repeated rounds of metastatic selection (LN1–LN4) progressively increased the epithelial phenotype, resulting in a new model of tumor cell mesenchy...

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Autori principali: Banyard, Jacqueline, Chung, Ivy, Wilson, Arianne M., Vetter, Guillaume, Le Béchec, Antony, Bielenberg, Diane R., Zetter, Bruce R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818652/
https://ncbi.nlm.nih.gov/pubmed/24193225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03151
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