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Regulation of epithelial plasticity by miR-424 and miR-200 in a new prostate cancer metastasis model

Using an in vivo cycling strategy, we selected metastatic cancer cells from the lymph nodes (LN) of mice bearing orthotopic DU145 human prostate tumors. Repeated rounds of metastatic selection (LN1–LN4) progressively increased the epithelial phenotype, resulting in a new model of tumor cell mesenchy...

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Bibliografiske detaljer
Main Authors: Banyard, Jacqueline, Chung, Ivy, Wilson, Arianne M., Vetter, Guillaume, Le Béchec, Antony, Bielenberg, Diane R., Zetter, Bruce R.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818652/
https://ncbi.nlm.nih.gov/pubmed/24193225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03151
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