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Discovery of Colorectal Cancer PIK3CA Mutation as Potential Predictive Biomarker: Power and Promise of Molecular Pathological Epidemiology

Regular use of aspirin reduces incidence and mortality of various cancers, including colorectal cancer. Anti-cancer effect of aspirin represents one of the “Provocative Questions” in cancer research. Experimental and clinical studies support a carcinogenic role for PTGS2 (cyclooxygenase-2), which is...

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Main Authors: Ogino, Shuji, Lochhead, Paul, Giovannucci, Edward, Meyerhardt, Jeffrey A, Fuchs, Charles S, Chan, Andrew T
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818472/
https://ncbi.nlm.nih.gov/pubmed/23792451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.244
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