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Molecular Pathologic Epidemiology of Colorectal Neoplasia: An Emerging Transdisciplinary and Interdisciplinary Field

Colorectal cancer is a complex disease resulting from somatic genetic and epigenetic alterations, including locus-specific CpG island methylation and global DNA or LINE-1 hypomethylation. Global molecular characteristics such as microsatellite instability (MSI), CpG island methylator phenotype (CIMP...

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Bibliographic Details
Main Authors: Ogino, Shuji, Chan, Andrew T., Fuchs, Charles S., Giovannucci, Edward
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040598/
https://ncbi.nlm.nih.gov/pubmed/21036793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2010.217182
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