Inhibiting AKT Phosphorylation Employing Non-Cytotoxic Anthraquinones Ameliorates T(H)2 Mediated Allergic Airways Disease and Rhinovirus Exacerbation

BACKGROUND: Severe asthma is associated with T helper (T(H)) 2 and 17 cell activation, airway neutrophilia and phosphoinositide-3-kinase (PI3K) activation. Asthma exacerbations are commonly caused by rhinovirus (RV) and also associated with PI3K-driven inflammation. Anthraquinone derivatives have be...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Cesar de Souza Alves, Caio, Collison, Adam, Hatchwell, Luke, Plank, Maximilian, Morten, Matthew, Foster, Paul S., Johnston, Sebastian L., França da Costa, Cristiane, Vieira de Almeida, Mauro, Couto Teixeira, Henrique, Paula Ferreira, Ana, Mattes, Joerg
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818233/
https://ncbi.nlm.nih.gov/pubmed/24223970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079565
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados