Selective Permeabilization of the Blood–Brain Barrier at Sites of Metastasis

BACKGROUND: Effective chemotherapeutics for primary systemic tumors have limited access to brain metastases because of the blood–brain barrier (BBB). The aim of this study was to develop a strategy for specifically permeabilizing the BBB at sites of cerebral metastases. METHODS: BALB/c mice were inj...

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Main Authors: Connell, John J., Chatain, Grégoire, Cornelissen, Bart, Vallis, Katherine A., Hamilton, Alastair, Seymour, Len, Anthony, Daniel C., Sibson, Nicola R.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818170/
https://ncbi.nlm.nih.gov/pubmed/24108809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt276
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