PP02. TOWARDS TNF TYPE-1 RECEPTOR SPECIFIC PERMEABILISATION OF THE BLOOD-BRAIN BARRIER IN BRAIN METASTASIS

The presence of an intact, impermeable blood-brain barrier (BBB) during the early (micrometastatic) stages of tumour development limits significantly both early detection and effective treatment of brain metastasis. Systemic administration of tumour necrosis factor (TNF) in murine models has been sh...

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Publicado en:Neuro Oncol
Main Authors: Karali, Ms Christina Simoglou, Soto, Dr Manuel Sarmiento, Economopoulos, Dr Vasiliki, Andreou, Ms Kleopatra, Anthony, Prof Daniel, Sibson, Prof Nicola R.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Abstracts
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358570/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now293.001
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