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Synthesis and characterization of mitoQ and idebenone analogues as mediators of oxygen consumption in mitochondria

Analogues of mitoQ and idebenone were synthesized to define the structural elements that support oxygen consumption in the mitochondrial respiratory chain. Eight analogues were prepared and fully characterized, then evaluated for their ability to support oxygen consumption in the mitochondrial respi...

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Detalhes bibliográficos
Main Authors: Duveau, Damien Y., Arce, Pablo M., Schoenfeld, Robert A., Raghav, Nidhi, Cortopassi, Gino A., Hecht, Sidney M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818132/
https://ncbi.nlm.nih.gov/pubmed/20691600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.06.104
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