The Mitochondria-targeted ubiquinone MitoQ decreases ethanol-dependent micro and macro hepatosteatosis

Chronic alcohol-induced liver disease results in inflammation, steatosis and increased oxidative and nitrosative damage to the mitochondrion. We hypothesized that targeting an antioxidant to the mitochondria would prevent oxidative damage and attenuate the steatosis associated with alcoholic liver d...

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Huvudupphovsmän: Chacko, Balu K, Srivastava, Anup, Johnson, Michelle, Benavides, Gloria A., Chang, Mi Jung, Ye, Yaozu, Jhala, Nirag, Murphy, Michael P, Kalyanaraman, Balaraman, Darley-Usmar, Victor M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125473/
https://ncbi.nlm.nih.gov/pubmed/21520201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24377
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