Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice

The polymorphic β-amyloid lesions present in individuals with Alzheimer’s disease are collectively known as cerebral β-amyloidosis. Amyloid precursor protein (APP) transgenic mouse models similarly develop β-amyloid depositions that differ in morphology, binding of amyloid conformation-sensitive dye...

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Main Authors: Heilbronner, Götz, Eisele, Yvonne S, Langer, Franziska, Kaeser, Stephan A, Novotny, Renata, Nagarathinam, Amudha, Åslund, Andreas, Hammarström, Per, Nilsson, K Peter R, Jucker, Mathias
Formato: Artigo
Idioma:Inglês
Publicado: European Molecular Biology Organization 2013
Assuntos:
Scientific Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818077/
https://ncbi.nlm.nih.gov/pubmed/23999102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.137
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