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Antimicrobial peptide β-defensin-1 expression is upregulated in Alzheimer’s brain

BACKGROUND: The human β-defensins (hBDs) are a highly conserved family of cationic antimicrobial and immunomodulatory peptides expressed primarily by epithelial cells in response to invasion by bacteria, fungi and some viruses. To date, the most studied members of this family of peptides are hBD-1,...

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Autori principali: Williams, Wesley M, Torres, Sandy, Siedlak, Sandra L, Castellani, Rudy J, Perry, George, Smith, Mark A, Zhu, Xiongwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817866/
https://ncbi.nlm.nih.gov/pubmed/24139179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-127
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